Paul Smyth made his return from injury in a 2-1 victory at MK Dons in Wanderers' final match of the Leasing.com Trophy group stage.
The QPR loanee entered the field at half-time at Stadium MK, and caught the eye with an explosive attacking display as Wanderers cancelled out Brennan Dickenson's expert free-kick with a stunning powerful drive from Bournemouth loanee Nnamdi Ofoborh.
Alex Samuel crashed an effort against the underside of the bar, Smyth was denied by Stuart Moore as he raced through one-on-one and Alex Pattison bent a chance narrowly over as Wycombe finished the game strongly.
With the game looking destined for a penalty shootout, Josh Parker thrashed home from 12 yards to secure the £10,000 prize money for the Chairboys and a winning end to their Trophy campaign.
Wycombe: Yates, Gardiner-Smith, Mascoll (Jacobson 90), Jombati, Phillips, Ofoborh, Pattison, Freeman, Samuel (Wheeler 73), Kashket (Smyth 45), Parker.
Unused subs: Allsop, Bloomfield, Thompson.