A deflected free-kick from Bryn Morris secured the Chairboys a narrow home victory against high-flying Peterborough United.
Fred Onyedinma was brought down on the edge of the penalty area, which saw Bryn Morris step up and score from the resulting set-piece 66 minutes into the second half.
After a cagey first half with few chances created from both sides, the scores were level going into the break, despite efforts from the likes of Onyedinma and Joe Jacobson.
Goalkeeper Ryan Allsop starred for the Chairboys making a number of important saves for Gareth Ainsworth's side.
Despite a nervy final few minutes, Wycombe's backline stood firm, which saw the Chairboys hold on to take all three points.
Gareth Ainsworth made four changes to his starting eleven from the weekend with Dominic Gape, Darius Charles, Randell Williams and Alex Samuel coming into the side, replacing Michael Harriman, Curtis Thompson, Craig Mackail-Smith and Adebayo Akinfenwa.
The visitors had an early opportunity to test the Chairboys’ backline six minutes in when Matt Godden fizzed a low cross into the penalty area, however the ball was unable to pick out the in-running Joe Ward, which eventually curled away from danger.
Wycombe’s first attempt on goal came a quarter of an hour in when Fred Onyedinma’s snapshot flew over the crossbar, failing to test Posh goalkeeper Aaron Chapman.
Chapman however was forced into making his first save of the afternoon 20 minutes in when he had to stretch and tip Joe Jacobson’s well-struck free-kick away for a corner.
Five minutes later saw an audacious cross-come-shot from Bryn Morris curl well away from goal just before Posh forward Ivan Toney’s strike from a tight angle hit the side netting.
The best chance of the first half came for the visitors 43 minutes in when Rhys Bennett found himself inside the box to strike at goal, however keeper Ryan Allsop got down well to deny the defender from breaking the deadlock.
Both sides went into half time knowing that they had to do a lot more to break down each other’s defensive units and find a way of taking the lead.
Ten minutes into the second half saw a header from Paris Cowan-Hall float just over the crossbar just moments before a brilliant chance fell to Posh striker Matt Godden when Toney slipped the striker in through on goal, however keeper Allsop did ever so well to stand his ground and make a brilliant save, tipping the ball away for a corner.
With the game still level, Onyedinma drove towards goal only to be taken down right on the edge of the penalty area by Ryan Tafazolli, who was booked for the foul.
From that resulting free-kick, the Chairboys took the lead 66 minutes in as Bryn Morris stepped up and rifled his shot through the wall, which took a deflection along the way, with the ball nestling into the bottom left corner.
Three minutes later, a deep cross from the far left by Alex Samuel had to be dealt with by keeper Chapman who managed to swat the ball away from soaring into the top left corner.
After doing ever so well to fill the void of target man Akinfenwa, Samuel was replaced 10 minutes from time by former Posh forward Craig Mackail-Smith.
Posh substitute Jason Cummings managed to get a shot away inside the penalty area, however his tame effort was comfortably saved low down by keeper Allsop.
Onyendinma then came close to doubling Wycombe’s lead when he tested goalkeeper Chapman late on from a tight angle inside the area, after he danced his way through the Posh backline.
Despite a nervy 5 minutes of stoppage time, the Chairboys were able to hold on to victory, seeing Gareth Ainsworth’s side win their fourth successive home match as well as keeping an impressive clean sheet against the league’s top scorers.