We pick out the facts and figures so you don't have to.We meet again
This will be the fifth encounter between the two clubs inside 15 months; the 2-2 draw at Adams Park last November was followed by 2-1 and 4-2 losses at Fratton Park in April and September, but the Chairboys were victorious in November, coming away from the south coast with a 2-1 FA Cup win.
Two points apart
Portsmouth sit sixth in League 2, just one place and two points ahead of the Wanderers. A home win would see the two clubs swap places.
Happy hunting ground
Portsmouth have enjoyed their three visits to Adams Park in league meetings; they won the first 1-0 with a highly contentious penalty, and left with draws on their last two trips, meaning they remain unbeaten in away games against the Chairboys.
Pompey have only played one match in the past fortnight; Wycombe have played four. Paul Cook's men had a game postponed at Crawley and also exited each cup competition at the first hurdle, meaning they could end the campaign playing the minimum 51 games. Wanderers could play as many as 61, having built up a hectic schedule of regular Tuesday-Saturday combinations by virtue of their recent cup exploits.
Both sides come into the game smarting from a defeat to Exeter in their last outing; Pompey lost 1-0 at Fratton Park last Saturday, while the Blues went down 4-2 in midweek.
Pompey suffered a 3-1 defeat to Doncaster in their last away game - prior to that, they hadn't lost on the road since the end of September. Wycombe remain unbeaten at home in the league since mid-October.
Alex Jakubiak could make his home debut after netting on his maiden appearance in Devon on Tuesday, having signed on loan from Watford until the end of the season. Portsmouth are likely to field prolific goalscorer Eoin Doyle, who signed on loan on deadline day from Preston after helping Chesterfield win promotion from League 1 three years ago, under Paul Cook's leadership.
The busy schedule prompted Gareth Ainsworth to make seven changes in midweek, leaving Joe Jacobson at home to rest while Paul Hayes and Adebayo Akinfenwa were left out as a precaution with slight knocks. Garry Thompson scored for the second game running so could keep his place up front, while Michael Harriman made his first appearance in over a month, now providing competition at right-back.
Marcus Bean was on loan at Portsmouth when he signed a permanent deal at Adams Park in January 2015, while Paris Cowan-Hall started his senior career at Fratton Park.
Man in the middle
Graham Salisbury is the referee for this match; he oversaw the 3-3 draw at Plymouth on Boxing Day.