By Sam AveryHaving lost to Bristol Rovers twice already this season, Wycombe made sure it wasn't three in three for the Pirates as Luke O'Nien's header late on earned Gareth Ainsworth's men a third win in four league games.
Marcus Bean had a glorious opportunity to open the scoring for the hosts early on but after fine build-up play down the right, Bean failed to convert Jacobson's low cross.
Then, more worryingly for Wycombe, Bean had to leave the field after picking up an injury and was replaced by Sam Wood.
The Chairboys managed a few more shots on goal before half-time, Steve Mildenhall comfortably saving O'Nien's left-footed shot from outside the box, before performing a more impressive stop to tip Jacobson's free-kick round the post.
Rovers were slow to get going in the game but almost found the opening goal early in the second half when Lee Brown's cross was flicked just wide by the head of Jermaine Easter from close range.
Ten minutes later, it was a set-piece that troubled the Wanderers defence as they failed to clear a Bristol Rovers corner. The ball made its way through the crowd of players into the box and Ryan Allsop prevented it from crossing the goal line.
It was constant pressure from the away side at this stage and once again Allsop was called into action to brilliantly tip over a long-range effort from Ollie Clarke.
The game was eventually decided five minutes from time when a Jacobson free-kick from just inside the Bristol Rovers half was launched into the area where it was met by the head of young O'Nien from close range, who guided the ball into the bottom corner and sent the supporters behind the goal in the Bucks New University stand into a frenzy of celebrations.
The three points mean Wycombe leapfrog Bristol Rovers in League Two and jump into 6th place.