Kortney Hause is set for a spell on the sidelines after sustaining an avulsion fracture of his left ankle.
The young centre-back will be assessed this week to determine the extent of the injury and how long he will be ruled out of action.
Fellow defender Nick Arnold has returned to parent club Reading for treatment after a reoccurrence of a groin injury.
Meanwhile, Gareth Ainsworth will be without strikers Jo Kuffour (thigh strain) and Jon-Paul Pittman (rolled ankle) for two weeks and 10 days respectively.