Gareth Ainsworth will be without Paris Cowan-Hall for three to four weeks after scans revealed the winger strained the medial ligament in his left knee on Saturday.
The 22-year-old was assessed on Monday after leaving the field on a stretcher following a heavy challenge midway through the second half.
Ainsworth said: “He’s strained some ligaments in his knee. It’s a big blow for us because he’s started the season very well, very exciting.
“He didn’t get too much ball on Saturday but we’ve watched the video back and Paris gives everything. His attitude’s first class.”