Wanderers struggled to create clear-cut chances as they slipped to a 3-0 defeat at Dagenham & Redbridge.
The Daggers took the lead in the 25 minute through Dwight Gayle’s close-range finish and despite a display full of passion and commitment from the Blues, they struggled in the final third.
A controversial Michael Spillane penalty made it 2-0 in the 55th minute before Billy Bingham wrapped up the points two minutes from time.
Youngsters Josh Scowen and Junior Morias both impressed for the Chairboys, but defensive lapses cost them.
Caretaker boss Gareth Ainsworth made three changes to the Wycombe side with Tottenham loanee Jordan Archer making his Wanderers debut and Josh Scowen and Olly Taylor in for their first Chairboys starts.
The hosts enjoyed more of the possession in the opening 10 minutes, but Wycombe looked comfortable in defence and saw out the early pressure well.
Olly Taylor had an effort well blocked before Dean Morgan’s 25-yard free-kick was superbly palmed away by Chris Lewington low to his left as the Chairboys grew into the contest. Josh Scott’s acrobatic volley, which comfortably cleared the bar, was the closest the hosts came in the opening 20 minutes.
However, it was Dagenham who took the lead five minutes later. Danny Foster conceded a free-kick on the Dagenham left and Luke Williams’ back-post header was well saved by Archer, only for Dwight Gayle to tap in from close-range.
Scott had an effort deflected straight at Archer following a quick counter-attack, but Wanderers were inches away from an equaliser seconds later when Matt Spring’s deflected strike was well parried behind for a corner.
Dagenham left-back Oluwafemi Ilesanmi had the final chance of the first half when the Chairboys backed off again, however, his 20-yard strike was comfortable for Archer.
Substitute Matt McClure had a chance to equalise with his first touch, but he toe-poked wide from eight yards following good link-up play with Morgan.
The hosts doubled their advantage in controversial circumstances 10 minutes after the break. Spring cleared a header off the line, but the assistant referee immediately raised his flag and a penalty was given. It was hard to see what the spot-kick was awarded for, but Michael Spillane made no mistake.
Gayle tested Archer again soon after and the lively McClure had another effort, this time forcing Lewington into a save at his near post.
Ainsworth threw on Joel Grant with 25 minutes remaining and he soon made an impact, hooking the ball goalwards but it also cleared the crossbar. Wycombe’s final throw of the dice came six minutes later when Junior Morias was introduced for his first professional start.
Morias looked a threat down the left and produced quality crosses into the box, but Dagenahm defended well and the Blues struggled to create clear chances.
McClure went close late on from Grant’s centre, but the Daggers added a third two minutes from time when Billy Bingham lashed home from close-range.
Wycombe: Archer, Foster, Dunne, Johnson, Doherty (c), Spring, Lewis, Scowen, Kuffour (Morias 71), Morgan (Grant 65), Taylor (McClure 46).
Subs: Harrison, Winfield, Kewley-Graham, Stewart.
Dagenham: Lewington, Ogogo (c), Ilesanmi, Wilkinson, Doe, Spillane, Howell, Bingham, Williams, Scott (Elito 77), Gayle (Woodall 82).
Subs: Seabright, Dominic Green, Reed, Hoyte, Danny Green.