Wanderers gave a good account of themselves in both matches against top-flight opposition and Waddock has challenged his squad to maintain that level at the Abbey Stadium (k.o. 3pm).
“The roles are reversed now,” said the Blues boss. “While our lads were trying to compete against the Fulhams and QPRs of this world and put on a good performance, Cambridge will be doing the same against us.
“We have to be totally professional in our attitude and we’ve already touched on that in our dressing room.
“We have to take what we did against QPR into the game on Saturday.”
Squad: Bull, Ingram, McCoy, Doherty, Stewart, Dunne, Basey, Grant, Wood, Bloomfield, Lewis, Spring, Angol, Oli, Beavon, Logan.
Chairboys fans will be housed in the South Stand and tickets for the fixture are priced at £12 for adults, £6 for concessions (students/over 60s/u16s) and free for U5s.
Address: Abbey Stadium, Newmarket Road, Cambridge, CB5 8LN
Can't make it to the Abbey Stadium?
Match updates will be provided via the club's Twitter feed - @wwfcofficial - plus there will be a report and reaction after the game.