Wanderers’ three-match winning run was brought to an end as two goals from Nathan Doyle and one from Will Atkinson earned Bradford a 3-0 victory.
Blues lacked a creative spark and struggled to test Bantams keeper Matt Duke as the visitors defended excellently throughout.
Gareth Ainsworth named an unchanged side following Saturday’s 4-0 victory over York with two-goal hero Dean Morgan and top scorer Matt McClure continuing in attack.
Bradford took the lead inside the opening 60 seconds when a long-throw in was cleared to the edge of the area where Nathan Doyle half-volleyed home.
Wanderers recovered well and Josh Scowen should have levelled in the fourth minute when he met Joel Grant’s inviting cross from the right, but he headed over the bar from six yards.
Bradford’s Andrew Davies almost headed into his own net from Scowen’s corner, but luckily for the centre-back it flew into the arms of former Wycombe loanee Matt Duke.
Morgan curled a 20-yard free-kick just the wrong side of the post in the 12th minute with Duke scrambling across the goal and struggling to get there.
Blues continued to create the better chances and Anthony Stewart headed another dangerous Scowen corner wide in the 19th minute after eluding his marker.
Garry Thompson had a low effort deflected out for a corner by Dave Winfield after the Chairboys struggled to deal with Kyel Reid’s deep cross. However, they went straight up the other end where Morgan drilled wide from the edge of the area.
Winfield headed another floated Scowen corner over the bar nine minutes before the break, before the latter picked up his 10th booking of the season and a two-game ban for a foul in midfield.
The final chance of the first half was for the Bantams as Will Atkinson sliced wide after a promising break.
The second half started as the first had ended with the Blues struggling to open up the visitors’ defence and the closest the came in the opening 10 minutes was when Morgan shot wide from an angle after McClure and Wood combined to find the forward.
Wanderers’ best move early on after the break came in the 58th minute when Scowen played Wood in on goal, but the ball was on the winger’s right foot and he shot at Duke who parried to safety.
Bradford were a coat of paint away from doubling their advantage in the 63rd minute when midfielder Garry Thompson’s dipping effort crashed back off the underside of the bar with Jordan Archer well beaten and Wycombe scrambled the ball away.
Substitute Bruno Andrade found space near to the byline in the 71st minute but he lacked support in the area and shot from a tight which and Duke comfortably saved.
The Bantams doubled their lead 10 minutes from time when Reid’s clever pass was hooked on by substitute James Hanson and Will Atkinson made no mistake, drilling past Archer from 10 yards.
It was 3-0 three minutes later when Hanson was brought down in the area and Doyle made no mistake from the spot, sending Archer the wrong way.
Duke denied the Chairboys a consolation a minute from time when he dived full length to his left to tip away Morgan’s deflected strike.
Grant had a 20-yard effort deflected wide in injury-time, but the Blues struggled to find a way past the Bradford defence.
Wanderers: Archer, Harriman, Dunne, Winfield (c), Stewart, Grant, Scowen, Lewis, Wood, Morgan, McClure (Andrade 69, Kuffour 86).
Subs: Harrison, Johnson, McCoy, Spring, Ainsworth, Kuffour.
Bradford: Duke, Darby, Dickson. Nelson, Davies (McHugh 86), Thompson, Jones (c), Doyle, Atkinson, Reid, Gray (Hanson 72).
Subs: McLaughlin, Hanson, Connell, Wells, Turgott, Good.
Attendance: 3,068 (444 Bradford)